Posted: July 22nd, 2021

NUR 302 Nursing : Evidence Based Practice


Proof based mostly observe (EBP) helps combine medical care with the purpose of bettering shoppers (sufferers) consequence (Parienti et al., 2012). As nurses proceed to grasp the observe, they're confronted with the issue of looking for the perfect proof to help each assessments and interventions, refine methods and develop new insurance policies as effectively. Though figuring out substantial proof from easier one is an advanced course of, a qualitative analysis methodology helps present invaluable information for the nurses of their observe. Marinho and da Cruz (2013) assert that qualitative analysis supplies its outcomes by way of participant’s phrases that may be simply utilized to the nursing care observe. Nevertheless, nurses are interested in this analysis since its strategies plus findings conform to the nursing observe the place understanding and figuring out the affected person wholly issues essentially the most. Finally, the first position of EBP is to offer the affected person with medical providers at a private degree. Aside from being steady, EBP additionally supplies dynamic integration of medical experience in addition to exterior proof in each day practices (O’grady et al., 2011).

 This essay discusses the query on whether or not using Chlorhexidine dressing decreases central venous catheter an infection charges (CVCIs) in comparison with standardized dressing in adults hospitalized in excessive complicated settings. Its rationale is that though a majority of vascular catheter –associated infections happens in individuals with extremely complicated settings, Chlorhexidine dressing can assist scale back the an infection charges.

Impression of Nursing Points on the Pupil MSN, FNP Specialty Monitor

Grasp of Science nursing abbreviated as MSN is a program that offers with the preparation of graduates for superior nursing observe in addition to doctoral examine, whereas household nurse practitioner (FNP) is a speciality monitor that helps learners broaden their nursing observe (Parienti et al., 2012). The monitor prepares nursing college students to handle healthcare wants of the sufferers, deal with promotion of well being and prevention of illnesses, analysis and administration of continual and acute sickness. Within the nursing faculty, Parienti et al., (2012) maintain that the practitioners do purchase each expertise and information wanted to carry out nursing assessments in addition to apply sequence of steps when conducting procedures. The MSN, FNP speciality monitor will subsequently present an FNP with the mandatory expertise to know using chlorhexidine (an antiseptic agent for pores and skin disinfection) and know whether or not it has any impact on the central venous catherization (CVC) such because the influence on infections.

 Lower than normal, outcomes reminiscent of pores and skin breakdown and infections would happen when a nurse skips steps of their procedures or haven't totally mastered the talents (Loveday et al., 2016). A lot of the instances, they draw information from previous instructional directions when making selections relating to efficiency of their practices. In keeping with Loveday et al., (2016), the monitor additionally assist nurses to synthesize information from humanities, sciences in addition to nursing theories to uphold superior nursing observe and develop sensible approaches of EBP together with nursing analysis. Most significantly, the FNP monitor would assist a learner perceive that vascular and CVC trigger extreme morbidities and mortality in aged sufferers. Additionally, they might be capable to look at the chlorhexidine (antiseptic agent) dressing results on the dangers of epidural in addition to catheter bacterial infections and colonization (Chan et al., 2012).

Proof Primarily based Measures Concerning the Use of Chlorhexidine to Scale back Central Venous Catheter Infections


 The essay describes the steps concerned in implementing an EBP mannequin for choice making at service ranges utilizing a case report. The essay additionally demonstrates findings of systematic evaluations evaluating the results of continued use of the Chlorhexidine in reducing CVCIs. The dressings are match on the entry websites of the central venous entry gadget (CVAD) and coated to guard them.

Theoretical Mannequin

The EBP mannequin helps in guiding the implementation of analysis into nursing observe utilizing needed procedures to enhance the consumer’s consequence (Garland et al., 2001). The mannequin is used to information the present case report.

Case Report

CVCIs are linked with mortality charges of over 12%.  As Kim et al., (2011) asserts, the accepted strategies of lowering catheter associated infections embrace use of acceptable options for the pores and skin antisepsis and entry of line, instant removing of pointless catheters and preferential subclavian catherization. Though dressings turn out to be indifferent in sufferers within the intensive care unit, lowering pores and skin colonization by micro organism on the web site of insertion through the use of antiseptic dressings can scale back the dangers of CVCI (Kim et al., 2011).  It has been proven that using chlorhexidine can lower a majority of catheter infections together with catheter associated blood infections (CRBI).

A PICO software was used to ask the next query: “Does using antiseptic chlorhexidine dressing lower central venous catherization an infection charges when in comparison with different standardized dressing in adults hospitalized in excessive complicated settings?”




In adults hospitalized in excessive complicated setting


Does antiseptic chlorhexidine


In contrast with standardized dressing


Efficient in lowering central venous catherization an infection charges

Conducting a Systematic Assessment

After figuring out the medical query, a literature search was performed finding a scientific overview. Use of systematic evaluations has been acknowledged in healthcare settings for informing medical questions. A metallic evaluation performed confirmed that use of chlorhexidine dressings favoured discount of CVI charges in adults than standardized dressings. The aim of reviewing was to check the variety of CVIs occurring in adults the place chlorhexidine was used in opposition to the variety of infections in individuals who used non-chlorhexidine dressing in figuring out the effectiveness of chlorhexidine to cut back the catheter colonization and an infection charges (Chan et al., 2012).

 A regular Cochrane collaboration methodology was used and search executed for related articles utilizing completely different databases reminiscent of Medline, CINAHL and EMBASE. Every paper was reviewed independently and management trials which the influence of chlorhexidine dressings was in comparison with a bunch that acquired standardized dressings.  Meta analyses had been performed utilizing consequence of the research. Luckily, the outcomes favoured use of chlorhexidine dressing on the entry websites of catheter to cut back CVI charges.

The forest plots evaluated use non-chlorhexidine in opposition to use of dressings and in contrast/contrasted prevalence’s of CRBI and catheter colonization between the teams (O’grady et al., 2011). No matter the methodological disparities between the research, heterogeneity of the Meta evaluation utilizing CRBI as the principle end result was zero.  Since hetegonitiy was far a lot excessive for catheter colonization, it could be thought of much less important. In keeping with Parienti et al., (20012), this insignificance confirmed that pooling of knowledge within the trials was needed. Nevertheless, the quantity wanted for treating evaluation to cut back CRBI was 62. Therefore, these dressings can be utilized to stop catheter colonization’s in each ten individuals.

Implications to the Scientific Apply

Nurse unit supervisor and nurse researcher mentioned consequence of the overview in addition to subsequent results for medical observe (Marinho and da Cruz, evaluation on this 2013). The overview favoured using chlorhexidine on lowering CVCI. Aside from the consideration of the proof, price evaluation was performed the place every dressing prices $6.00 and wanted to be modified twenty-four hours following catheter insertion. As per the native database, the typical size of time that the central venous entry gadget was in situ in adults hospitalized in ICU was 29 days and would requires six dressing throughout the interval, therefore  price of stopping one episode of CRBI was very excessive. To summarize, this overview concluded that chlorhexidine dressing supplies easy but price efficient methodology of lowering the incidences of CRBI occurring in grownup sufferers.


A scientific overview of this report confirmed chlorhexidine dressings as price efficient but easy medical intervention of lowering CVCIs incidences in grownup sufferers. Additionally, the case report confirmed that the issues encountered by the Clinicals had been in making selections based mostly proof. Although there are frameworks obtainable to facilitate EBP, the case report confirmed a doable operationalization of a collaborative mannequin. Nevertheless, the mannequin was a key to the success of medical circumstances among the many nurse directors, medical nurse plus the researchers. As Kim et al., (2011) asserts it is usually essential to acknowledge that there have been randomized management trials obtainable for evaluation.

In situations the place sufficient proof can't be discovered, it's smart to attend for proof from major analysis earlier than the observe change. Nevertheless, the scope of the essay is confined to a report of EBP course of however failed to search out the observe change results relating to the medical consequence. Therefore, this report presents the steps for EBP and supplies rational and evaluation of cost-effectiveness estimation for proofing the observe change. Additionally, it’s famous that in an excellent state of affairs, the reviewing performed within the EBP must be peer reviewed.


A analysis utilization collaborative methodology in healthcare is acceptable to tell the dressings observe in addition to guarantee its effectiveness is delivered with the purpose of bettering healthcare’s consequence. A pleasant surroundings and infrastructure for enquiries in medical in addition to analysis are recognized to allow implementation of the EBP.  Subsequently, it has been evident from the evaluation that using antiseptic chlorhexidine dressing reduces central venous catherization an infection charges when in comparison with standardized dressings in adults hospitalized in excessive complicated settings.  


Chan, R., Northfield, S., Alexander, A., & Rickard, C. (2012). Utilizing the collaborative proof based mostly observe mannequin: a scientific overview and uptake of chlorhexidine-impregnated sponge dressings on central venous entry units in a tertiary most cancers centre. Australian Journal of Most cancers Nursing, 13(2), 10-15.

Frasca, D., Dahyot-Fizelier, C., & Mimoz, O. (2010). Prevention of central venous catheter-related an infection within the intensive care unit. Important care, 14(2), 212.

Garland, J. S., Alex, C. P., Mueller, C. D., Otten, D., Shivpuri, C., Harris, M. C., ... & Goldmann, D. A. (2001). A randomized trial evaluating povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates. Pediatrics, 107(6), 1431-1436.

Kim, J. S., Holtom, P., & Vigen, C. (2011). Discount of catheter-related bloodstream infections by way of using a central venous line bundle: epidemiologic and financial penalties. American journal of an infection management, 39(eight), 640-646.

Loveday, H. P., Wilson, J. A., Prieto, J., & Wilcox, M. H. (2016). epic3: revised advice for intravenous catheter and catheter web site care. Journal of Hospital An infection, 92(four), 346-348.

Marinho, J. S., & da Cruz, I. C. (2013). Discount of an infection related to central venous catheterization by antiseptics-Sistematic Literature Assessment. Journal of Specialised Nursing Care, 6(1).

O'grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., ... & Raad, I. I. (2011). Tips for the prevention of intravascular catheter-related infections. Scientific infectious illnesses, 52(9), e162-e193.

Parienti, J. J., du Cheyron, D., Timsit, J. F., Traoré, O., Kalfon, P., Mimoz, O., & Mermel, L. A. (2012). Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated an infection threat discount in critically unwell adults. Important care medication, 40(5), 1627-1634.

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